Opioid Reduction
Study register · detail Querschnittssurvey (Real-World-Daten) · Opioid Reduction · 2017

Cannabis as a Substitute for Opioid-Based Pain Medication: Patient Self-Report

Clear benefit GRADE Low 243 citations
Samplen = 2.897 Pat.
Durationpast 6 months
EndpointSelf-reported opioid…
Blindingn.a.
DesignQuerschnittssurvey (Real-World-Daten)
Cannabinoidvollspektrum
Key finding

The large majority of respondents reported being able to reduce opioid use through cannabis and perceiving cannabis as sole therapy to be more effective.

Summary

n=2.897 medical cannabis patients; 34% used opioid-based pain medication in the past 6 months; 97% agreed they could reduce opioid dose while using cannabis concurrently; 81% reported cannabis alone more effective than cannabis+opioids. Self-report data without controlled comparison.

P
PopulationMedical cannabis patients, n=2897, of whom 34% with opioid use in the past 6 months
I
InterventionMedical cannabis (various forms of administration, self-report)
O
Outcome97% agreed/strongly agreed that they could reduce the amount of opioids while using cannabis concurrently; 81% reported that cannabis alone was more effective than cannabis in combination with opioids
Confidence in the evidence
Low

The second of four GRADE levels, the effect estimate is of limited reliability.

Quality profile
Sample size
Blinding
Effect size Clear benefit
Citations / year
Authors
Reiman A, Welty M, Solomon P
DOI 10.1089/can.2017.0012
Design: Querschnittssurvey (Real-World-Daten)
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Abstract
<b>Introduction:</b> Prescription drug overdoses are the leading cause of accidental death in the United States. Alternatives to opioids for the treatment of pain are necessary to address this issue. Cannabis can be an effective treatment for pain, greatly reduces the chance of dependence, and eliminates the risk of fatal overdose compared to opioid-based medications. Medical cannabis patients report that cannabis is just as effective, if not more, than opioid-based medications for pain. <b>Materials and Methods:</b> The current study examined the use of cannabis as a substitute for opioid-based pain medication by collecting survey data from 2897 medical cannabis patients. <b>Discussion</b>: Thirty-four percent of the sample reported using opioid-based pain medication in the past 6 months. Respondents overwhelmingly reported that cannabis provided relief on par with their other medications, but without the unwanted side effects. Ninety-seven percent of the sample "strongly agreed/agreed" that they are able to decrease the amount of opiates they consume when they also use cannabis, and 81% "strongly agreed/agreed" that taking cannabis by itself was more effective at treating their condition than taking cannabis with opioids. Results were similar for those using cannabis with nonopioid-based pain medications. <b>Conclusion:</b> Future research should track clinical outcomes where cannabis is offered as a viable substitute for pain treatment and examine the outcomes of using cannabis as a medication assisted treatment for opioid dependence.

The impediment to action advances action. — Marcus Aurelius