Opioid Reduction
Study register · detail Kohortenstudie · Opioid Reduction · 2022

Medical Cannabis Patients Report Improvements in Health Functioning and Reductions in Opiate Use

Clear benefit GRADE Low 23 citations
Samplen = 2.183 Pat.
DurationCross-sectional study
EndpointSF-36
Blindingn.a.
DesignKohortenstudie
Cannabinoidvollspektrum
Key finding

Patients reported improvements in the domains of bodily pain, physical functioning and social functioning after initiation of medical cannabis; 79% showed reduction or cessation of opioid medication.

Summary

Survey of medical cannabis patients on self-reported improvements in health functions and opioid reduction; real-world data, but without controlled design or objective measurement of opioid consumption.

P
PopulationAdult medical cannabis patients in Florida, n=2.183, predominantly 20-70 years, 54% female, most common indications: pain+mental illness (48%), mental illness (29%), pain (9%)
I
InterventionMedical cannabis (various forms of administration from dispensaries)
O
Outcome61% reported prior opiate use, of whom 79% reduction/cessation after cannabis initiation; improvements in SF-36 domains (pain, physical/social function), no deterioration in quality of life
Confidence in the evidence
Low

The second of four GRADE levels, the effect estimate is of limited reliability.

Quality profile
Sample size
Blinding
Effect size Clear benefit
Citations / year
Authors
Pritchett C E, Flynn H, Wang Y et al.
DOI 10.1080/10826084.2022.2107673
Design: Kohortenstudie
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Abstract
Purpose: Opioid use rates have dropped as North American patients gain access to medical cannabis, indicating a harm reduction role, yet health outcomes remain mostly unexplored. This study presents self-reported medical cannabis use, perceptions of health functioning, and changes in opioid pain medication use in Florida medical cannabis patients.Methods: Patients (n = 2,183) recruited from medical dispensaries across Florida completed a 66-item cross-sectional survey that included demographic, health, and medication usage items, along with items from the Medical Outcomes Survey (SF-36) to assess health functioning before and after cannabis initiation.Results: Most participants were between the ages of 20 and 70 years of age (95%), over 54% were female, 47% were employed, and most (85%) were white. Commonly reported ailment groups were Pain and Mental Health combined (47.92%), Mental Health (28.86%) or Pain (9.07%). Health domains of bodily pain, physical functioning, and social functioning improved while limitations due to physical and emotional problems were unchanged. Most patients rated medical cannabis as being important to their quality of life. Many (60.98%) reported using pain medications prior to medical cannabis, 93.36% of these reported a change in pain medication after medical cannabis. The majority of participants (79%) reported either cessation or reduction in pain medication use following initiation of medical cannabis and 11.47% described improved functioning.Conclusions: The findings suggest that some medical cannabis patients decreased opioid use without harming quality of life or health functioning, soon after the legalization of medical cannabis. The public health implications of medical cannabis as an alternative pain medication are discussed.

The impediment to action advances action. — Marcus Aurelius