←PTSD

Study register · detail Retrospektive Chartanalyse (Real-World-Register) · PTSD · 2014

PTSD symptom reports of patients evaluated for the New Mexico Medical Cannabis Program.

Greer et al. ·Dialnet (Universidad de la Rioja)

Clear benefit GRADE Very low 0 citations

Samplen = 80 Pat.

Duration2009 to 2011

EndpointCAPS

Blindingn.a.

DesignRetrospektive Chartanalyse (Real-World-Register)

Key finding

Cannabis was associated with a more than 75% reduction in PTSD symptom severity according to CAPS.

Summary

n=80 PTSD patients (New Mexico Medical Cannabis Program, 2009–2011); CAPS score comparison with cannabis vs. without cannabis: >75% reduction in PTSD symptom scores with cannabis use. Retrospective, uncontrolled survey; prospective RCTs pending.

PopulationAdults with PTSD who applied for the New Mexico Medical Cannabis Program, n=80

InterventionMedical cannabis (type, dose, route of administration not specified)

OutcomeReduction in CAPS total scores by more than 75% during cannabis use compared with non-use

Confidence in the evidence

Very low

The lowest GRADE level, the effect estimate remains uncertain.

Downgraded for

Imprecision

Quality profile

Sample size ★★★★★

Blinding —

Effect size Clear benefit

Citations / year ★★★★★

Authors

Greer GR, Grob CS, Halberstadt AL.

DOI 10.1080/02791072.2013.873843↗

Design: Retrospektive Chartanalyse (Real-World-Register)

Abstract

<h4>Background</h4>New Mexico was the first state to list post-traumatic stress disorder (PTSD) as a condition for the use of medical cannabis. There are no published studies, other than case reports, of the effects of cannabis on PTSD symptoms. The purpose of the study was to report and statistically analyze psychometric data on PTSD symptoms collected during 80 psychiatric evaluations of patients applying to the New Mexico Medical Cannabis Program from 2009 to 2011.<h4>Methods</h4>The Clinician Administered Posttraumatic Scale for DSM-IV (CAPS) was administered retrospectively and symptom scores were then collected and compared in a retrospective chart review of the first 80 patients evaluated.<h4>Results</h4>Greater than 75% reduction in CAPS symptom scores were reported when patients were using cannabis compared to when they were not.<h4>Conclusions</h4>Cannabis is associated with reductions in PTSD symptoms in some patients, and prospective, placebo-controlled study is needed to determine efficacy of cannabis and its constituents in treating PTSD.

The impediment to action advances action. — Marcus Aurelius