Palliative Care
Study register · detail Narrative Review · Palliative Care · 2019

Cannabis und Cannabinoide in der Palliativversorgung

Unclear 4 citations
SampleNarrative Review
Blindingunklar
DesignNarrative Review
Key finding

There is no high-quality evidence for the use of cannabis and cannabinoids in palliative care; they could be considered as a therapeutic trial for cancer pain, HIV-associated weight gain, and other symptoms, if established treatments fail.

Summary

Narrative review on cannabis/cannabinoids in palliative care, focused on the Mücke et al. SR. Conclusion: overall no high-quality evidence; cannabinoids may be considered as a therapeutic trial for tumor pain, weight gain (HIV), as well as nausea/loss of appetite, if established therapies fail. Further studies with larger patient numbers required; special conditions of palliative medicine make high-quality studies difficult.

SummaryNarrative review on the current evidence for cannabis and cannabinoids in palliative care: overall no high-quality evidence; cannabinoids may be considered as a therapeutic trial for cancer pain, weight gain in HIV, and nausea and loss of appetite, if established therapies fail.
Quality profile
Sample size
Blinding
Effect size
Citations / year
Authors
Rasche T, Emmert D, Radbruch L, Conrad R, Mücke M
DOI 10.1007/s00103-019-02967-1
Design: Narrative Review
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Abstract
Cannabis and cannabinoids are discussed as a potential treatment for a broad spectrum of diseases and symptoms. This article presents current evidence for the use of cannabis and cannabinoids in palliative care and delivers background information. For this purpose recent literature was examined and evaluated. The authors focused on a systematic review and meta-analysis of cannabinoids in palliative care by Mucke et al.Overall, there is no high-quality evidence for the use of cannabis and cannabinoids in palliative care. Cannabinoids may be considered as a therapeutic attempt in the treatment of cancer pain and weight gain in patients with HIV as well as other symptoms (such as nausea and loss of appetite) if established treatments fail.Further studies involving more patients are needed to evaluate the therapeutic potential of cannabis and cannabinoids. However, special conditions in the field of palliative care make it difficult to carry out high-quality studies.

The impediment to action advances action. — Marcus Aurelius